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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | P-selectin | ||
| Ligand | BDBM50425873 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_933984 (CHEMBL2318062) | ||
| IC50 | 1100±n/a nM | ||
| Citation |  Powell, NA; Hoffman, JK; Ciske, FL; Kohrt, JT; Baxi, SM; Peng, YW; Zhong, M; Catana, C; Ohren, J; Perrin, LA; Edmunds, JJ Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase. Bioorg Med Chem Lett23:1051-5 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| P-selectin | |||
| Name: | P-selectin | ||
| Synonyms: | GMRP | GRMP | LYAM3_HUMAN | P-selectin | P-selectin/P-selectin glycoprotein ligand 1 | SELP | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 90834.61 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1438999 | ||
| Residue: | 830 | ||
| Sequence: |
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| BDBM50425873 | |||
| n/a | |||
| Name | BDBM50425873 | ||
| Synonyms: | CHEMBL2312648 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H37Cl2N7O | ||
| Mol. Mass. | 534.524 | ||
| SMILES | CN(C)C1CCC(CC1)Nc1nc(NCc2cc(Cl)ccc2Cl)ncc1C(=O)NC1CCN(C)CC1 |(25.27,-50.31,;26.81,-50.32,;27.57,-51.65,;27.59,-48.99,;26.83,-47.65,;27.6,-46.32,;29.13,-46.34,;29.91,-47.66,;29.13,-49,;29.91,-45.01,;29.14,-43.67,;27.6,-43.67,;26.84,-42.33,;25.3,-42.33,;24.53,-43.66,;22.99,-43.66,;22.22,-44.99,;20.69,-44.99,;19.92,-46.32,;19.91,-43.65,;20.69,-42.32,;22.22,-42.32,;23,-40.99,;27.6,-41,;29.14,-41,;29.91,-42.34,;31.45,-42.34,;32.22,-43.67,;32.23,-41.01,;33.77,-41.01,;34.53,-42.34,;36.06,-42.35,;36.84,-41.02,;38.38,-41.03,;36.07,-39.68,;34.53,-39.67,)| | ||
| Structure | 
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