Ki Summary

Reaction Details

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Target

Cannabinoid receptor 2

Ligand

BDBM50426108

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_935496 (CHEMBL2319555)

12±n/a nM

Citation

Aghazadeh Tabrizi, M; Baraldi, PG; Saponaro, G; Moorman, AR; Romagnoli, R; Preti, D; Baraldi, S; Corciulo, C; Vincenzi, F; Borea, PA; Varani, K Design, synthesis, and pharmacological properties of new heteroarylpyridine/heteroarylpyrimidine derivatives as CB(2) cannabinoid receptor partial agonists. J Med Chem56:1098-112 (2013) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Cannabinoid receptor 2

Name:

Cannabinoid receptor 2

Synonyms:

CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2

Type:

Enzyme

Mol. Mass.:

39366.68

Organism:

Rattus norvegicus (Rat)

Description:

Q9QZN9

Residue:

360

Sequence:

MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILS
SQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLD
VRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYA
LRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC

BDBM50426108

n/a

Name

BDBM50426108

Synonyms:

CHEMBL2316297

Type

Small organic molecule

Emp. Form.

C21H32N4O2

Mol. Mass.

372.5044

SMILES

CCCCCn1cc(C(=O)N[C@@H]2CC[C@H](C)CC2)c(=O)c2c(C)nn(C)c12 |r,wU:11.10,14.14,(14.6,-37.76,;14.6,-36.22,;15.93,-35.45,;15.93,-33.91,;17.27,-33.14,;17.27,-31.6,;18.59,-30.84,;18.59,-29.3,;19.93,-28.53,;19.94,-26.99,;21.26,-29.31,;21.26,-30.85,;19.91,-31.61,;19.9,-33.15,;21.23,-33.93,;21.22,-35.47,;22.57,-33.16,;22.58,-31.62,;17.27,-28.52,;17.27,-26.98,;15.94,-29.3,;14.47,-28.82,;14,-27.36,;13.57,-30.07,;14.47,-31.31,;14,-32.78,;15.94,-30.84,)|

Structure