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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cell division cycle 7-related protein kinase | ||
| Ligand | BDBM50426463 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_940355 (CHEMBL2328973) | ||
| Ki | 5.5±n/a nM | ||
| Citation |  Tong, Y; Stewart, KD; Florjancic, AS; Harlan, JE; Merta, PJ; Przytulinska, M; Soni, N; Swinger, KK; Zhu, H; Johnson, EF; Shoemaker, AR; Penning, TD Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195. ACS Med Chem Lett4:211-5 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cell division cycle 7-related protein kinase | |||
| Name: | Cell division cycle 7-related protein kinase | ||
| Synonyms: | CDC7 | CDC7-related kinase | CDC7L1 | CDC7_HUMAN | Cell division cycle 7-related protein kinase (CDC7) | HsCdc7 | huCdc7 | ||
| Type: | Protein | ||
| Mol. Mass.: | 63908.16 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00311 | ||
| Residue: | 574 | ||
| Sequence: |
| ||
| BDBM50426463 | |||
| n/a | |||
| Name | BDBM50426463 | ||
| Synonyms: | CHEMBL2322675 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H19N5O | ||
| Mol. Mass. | 333.3871 | ||
| SMILES | O[C@H]1CC[C@@H](CC1)Nc1cc(cc(n1)C#N)-c1c[nH]c2ncccc12 |r,wU:4.7,wD:1.0,(19.06,-40.41,;17.72,-41.18,;16.38,-40.41,;15.04,-41.18,;15.06,-42.71,;16.39,-43.49,;17.71,-42.72,;13.73,-43.48,;12.39,-42.72,;11.05,-43.49,;9.72,-42.72,;9.72,-41.17,;11.05,-40.4,;12.39,-41.17,;11.04,-38.87,;11.03,-37.33,;8.39,-43.49,;8.22,-45.02,;6.72,-45.34,;5.94,-44,;4.44,-43.69,;3.97,-42.23,;5,-41.08,;6.5,-41.4,;6.98,-42.86,)| | ||
| Structure | 
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