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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cell division cycle 7-related protein kinase | ||
| Ligand | BDBM50426466 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_940355 (CHEMBL2328973) | ||
| Ki | 3.4±n/a nM | ||
| Citation |  Tong, Y; Stewart, KD; Florjancic, AS; Harlan, JE; Merta, PJ; Przytulinska, M; Soni, N; Swinger, KK; Zhu, H; Johnson, EF; Shoemaker, AR; Penning, TD Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195. ACS Med Chem Lett4:211-5 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cell division cycle 7-related protein kinase | |||
| Name: | Cell division cycle 7-related protein kinase | ||
| Synonyms: | CDC7 | CDC7-related kinase | CDC7L1 | CDC7_HUMAN | Cell division cycle 7-related protein kinase (CDC7) | HsCdc7 | huCdc7 | ||
| Type: | Protein | ||
| Mol. Mass.: | 63908.16 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00311 | ||
| Residue: | 574 | ||
| Sequence: |
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| BDBM50426466 | |||
| n/a | |||
| Name | BDBM50426466 | ||
| Synonyms: | CHEMBL2322684 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H20FN5 | ||
| Mol. Mass. | 325.3833 | ||
| SMILES | N[C@H]1CC[C@@H](CC1)Nc1cc(cc(F)n1)-c1c[nH]c2ncccc12 |r,wU:4.7,wD:1.0,(17.72,-27.15,;16.38,-27.92,;15.05,-27.15,;13.71,-27.92,;13.73,-29.45,;15.05,-30.23,;16.38,-29.46,;12.39,-30.23,;11.06,-29.46,;9.72,-30.23,;8.39,-29.46,;8.39,-27.91,;9.72,-27.14,;9.71,-25.6,;11.05,-27.91,;7.05,-30.23,;6.89,-31.76,;5.38,-32.08,;4.61,-30.75,;3.11,-30.43,;2.63,-28.97,;3.67,-27.82,;5.17,-28.14,;5.64,-29.6,)| | ||
| Structure | 
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