| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cell division cycle 7-related protein kinase |
|---|
| Ligand | BDBM50365695 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_940355 (CHEMBL2328973) |
|---|
| Ki | 0.280000±n/a nM |
|---|
| Citation |  Tong, Y; Stewart, KD; Florjancic, AS; Harlan, JE; Merta, PJ; Przytulinska, M; Soni, N; Swinger, KK; Zhu, H; Johnson, EF; Shoemaker, AR; Penning, TD Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195. ACS Med Chem Lett4:211-5 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cell division cycle 7-related protein kinase |
|---|
| Name: | Cell division cycle 7-related protein kinase |
|---|
| Synonyms: | CDC7 | CDC7-related kinase | CDC7L1 | CDC7_HUMAN | Cell division cycle 7-related protein kinase (CDC7) | HsCdc7 | huCdc7 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 63908.16 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O00311 |
|---|
| Residue: | 574 |
|---|
| Sequence: | MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKI
EDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGV
KYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKP
SNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSG
PVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISH
ESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVC
SICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDD
LTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQ
GHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPD
EAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL
|
|
|
|---|
| BDBM50365695 |
|---|
| n/a |
|---|
| Name | BDBM50365695 |
|---|
| Synonyms: | CHEMBL1958408 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N4O |
|---|
| Mol. Mass. | 308.3776 |
|---|
| SMILES | O=c1cc(cc(NC2CCCCC2)[nH]1)-c1c[nH]c2ncccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
