| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein-arginine deiminase type-4 |
|---|
| Ligand | BDBM50355657 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_938239 (CHEMBL2328662) |
|---|
| IC50 | 5900±n/a nM |
|---|
| Citation |  Bello, AM; Wasilewski, E; Wei, L; Moscarello, MA; Kotra, LP Interrogation of the Active Sites of Protein Arginine Deiminases (PAD1, -2, and -4) Using Designer Probes. ACS Med Chem Lett4:249-53 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein-arginine deiminase type-4 |
|---|
| Name: | Protein-arginine deiminase type-4 |
|---|
| Synonyms: | PAD4 | PADI4 | PADI4_HUMAN | PADI5 | PDI5 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 74078.90 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_216548487 |
|---|
| Residue: | 663 |
|---|
| Sequence: | MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK
KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD
ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM
SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV
PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP
NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP
HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG
KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP
APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS
FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK
PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN
MVP
|
|
|
|---|
| BDBM50355657 |
|---|
| n/a |
|---|
| Name | BDBM50355657 |
|---|
| Synonyms: | CHEMBL1910972 | CHEMBL1962361 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H19ClN4O2 |
|---|
| Mol. Mass. | 310.779 |
|---|
| SMILES | NC(=O)[C@H](CCCN=C(N)CCl)NC(=O)c1ccccc1 |r,w:7.6| |
|---|
| Structure | 
|
|---|
Search and Browse
