| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-10 |
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| Ligand | BDBM50426565 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938626 (CHEMBL2327246) |
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| IC50 | 3300±n/a nM |
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| Citation |  Rosse, G Irreversible inhibitors of cysteine proteases. ACS Med Chem Lett4:163-4 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-10 |
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| Name: | Caspase-10 |
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| Synonyms: | CASP10 | CASPA_HUMAN | MCH4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 58956.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92851 |
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| Residue: | 521 |
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| Sequence: | MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRMLKFLEKT
MEIRGRKRTVWGAKQISATSLPTAISAQTPRPPMRRWSSVS
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| BDBM50426565 |
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| n/a |
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| Name | BDBM50426565 |
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| Synonyms: | CHEMBL2324340 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H46N6O10S |
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| Mol. Mass. | 754.85 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(O)=O)C=CS(C)(=O)=O |r,w:48.51| |
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| Structure | 
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