| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-10 |
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| Ligand | BDBM50426564 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938626 (CHEMBL2327246) |
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| IC50 | 2670±n/a nM |
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| Citation |  Rosse, G Irreversible inhibitors of cysteine proteases. ACS Med Chem Lett4:163-4 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-10 |
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| Name: | Caspase-10 |
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| Synonyms: | CASP10 | CASPA_HUMAN | MCH4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 58956.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92851 |
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| Residue: | 521 |
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| Sequence: | MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRMLKFLEKT
MEIRGRKRTVWGAKQISATSLPTAISAQTPRPPMRRWSSVS
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| BDBM50426564 |
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| n/a |
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| Name | BDBM50426564 |
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| Synonyms: | CHEMBL2323966 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H33ClN4O7S |
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| Mol. Mass. | 557.059 |
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| SMILES | CC(C)(C)[C@@H](NC(=O)c1ccc(N)c(Cl)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)\C=C\S(C)(=O)=O |r| |
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| Structure | 
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