| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-4 |
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| Ligand | BDBM50426562 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938632 (CHEMBL2327252) |
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| IC50 | 370±n/a nM |
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| Citation |  Rosse, G Irreversible inhibitors of cysteine proteases. ACS Med Chem Lett4:163-4 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-4 |
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| Name: | Caspase-4 |
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| Synonyms: | CASP-4 | CASP4 | CASP4_HUMAN | Caspase 4 | Caspase-4 subunit 1 | Caspase-4 subunit 2 | ICE(rel)-II | ICH-2 protease | ICH2 | TX protease |
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| Type: | Enzyme |
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| Mol. Mass.: | 43257.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49662 |
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| Residue: | 377 |
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| Sequence: | MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADS
MQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGPPESGESTDALKLCPHEEFLRLCKE
RAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGADFDITGMKELLEGLDYSVDVEENLT
ARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHDEKKPDVLLYDTIFQIFNN
RNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQSSENLEEDAVYKTHVEKDF
IAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEEVFRKVQQSFETPRAKAQMP
TIERLSMTRYFYLFPGN
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| BDBM50426562 |
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| n/a |
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| Name | BDBM50426562 |
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| Synonyms: | CHEMBL2324339 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H45N5O10S |
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| Mol. Mass. | 667.771 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](CC(O)=O)C=CS(C)(=O)=O |r,w:41.42| |
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| Structure | 
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