| Reaction Details |
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 | Report a problem with these data |
| Target | KCNQ (Kv7) potassium channel |
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| Ligand | BDBM50426567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938652 |
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| EC50 | 2400±n/a nM |
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| Citation |  Bagal SK; Brown AD; Cox PJ; Omoto K; Owen RM; Pryde DC; Sidders B; Skerratt SE; Stevens EB; Storer RI; Swain NA Ion channels as therapeutic targets: a drug discovery perspective. J Med Chem 56:593-624 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| KCNQ (Kv7) potassium channel |
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| Name: | KCNQ (Kv7) potassium channel |
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| Synonyms: | Voltage-gated potassium channel subunit Kv7.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96759.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_938652 |
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| Residue: | 872 |
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| Sequence: | MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG
ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG
WALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAS
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA
YAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPR
NEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPT
KGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNL
PRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRR
SITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDT
DTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI
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| BDBM50426567 |
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| n/a |
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| Name | BDBM50426567 |
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| Synonyms: | BMS-204352 | FLINDOKALNER | MaxiPost |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10ClF4NO2 |
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| Mol. Mass. | 359.703 |
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| SMILES | COc1ccc(Cl)cc1[C@]1(F)C(=O)Nc2cc(ccc12)C(F)(F)F |
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| Structure | 
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