| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Inward rectifier potassium channel 4 |
|---|
| Ligand | BDBM50426568 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_938655 (CHEMBL2327427) |
|---|
| IC50 | 24000±n/a nM |
|---|
| Citation |  Bagal, SK; Brown, AD; Cox, PJ; Omoto, K; Owen, RM; Pryde, DC; Sidders, B; Skerratt, SE; Stevens, EB; Storer, RI; Swain, NA Ion channels as therapeutic targets: a drug discovery perspective. J Med Chem56:593-624 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Inward rectifier potassium channel 4 |
|---|
| Name: | Inward rectifier potassium channel 4 |
|---|
| Synonyms: | HIR | HIRK2 | HRK1 | Hippocampal inward rectifier | IRK-3 | IRK3 | Inward rectifier K(+) channel Kir2.3 | KCNJ4 | KCNJ4_HUMAN | Potassium channel, inwardly rectifying subfamily J member 4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49496.50 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1515519 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM
IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG
FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK
RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR
DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV
LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG
SHLDLERMQASLPLDNISYRRESAI
|
|
|
|---|
| BDBM50426568 |
|---|
| n/a |
|---|
| Name | BDBM50426568 |
|---|
| Synonyms: | CHEMBL2324345 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H26N4O2 |
|---|
| Mol. Mass. | 366.4567 |
|---|
| SMILES | OC(CN1CCOCC1)Cn1c2ccccc2n(Cc2ccccc2)c1=N |
|---|
| Structure | 
|
|---|
Search and Browse
