| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50426619 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_939354 (CHEMBL2327489) |
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| Ki | 0.160000±n/a nM |
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| Citation |  Jørgensen, M; Jørgensen, PN; Christoffersen, CT; Jensen, KG; Balle, T; Bang-Andersen, B Discovery of novela1-adrenoceptor ligands based on the antipsychotic sertindole suitable for labeling as PET ligands. Bioorg Med Chem21:196-204 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_BOVIN | ADRA1A | ADRA1C | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha-1C adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51492.08 |
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| Organism: | CALF |
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| Description: | adrenergic Alpha1 0 CALF |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
AQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTL
HAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACT
TARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV
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| BDBM50426619 |
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| n/a |
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| Name | BDBM50426619 |
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| Synonyms: | CHEMBL2326175 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24FN5 |
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| Mol. Mass. | 389.4686 |
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| SMILES | CN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)-c1ncn(C)n1 |
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| Structure | 
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