| Reaction Details |
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 | Report a problem with these data |
| Target | D-amino-acid oxidase |
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| Ligand | BDBM31147 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938788 (CHEMBL2327932) |
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| IC50 | 177±n/a nM |
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| Citation |  Katane, M; Osaka, N; Matsuda, S; Maeda, K; Kawata, T; Saitoh, Y; Sekine, M; Furuchi, T; Doi, I; Hirono, S; Homma, H Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro. J Med Chem56:1894-907 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-amino-acid oxidase |
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| Name: | D-amino-acid oxidase |
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| Synonyms: | D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN |
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| Type: | Homodimer |
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| Mol. Mass.: | 39476.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14920 |
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| Residue: | 347 |
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| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
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| BDBM31147 |
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| n/a |
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| Name | BDBM31147 |
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| Synonyms: | 4H-furo[3,2-b]pyrrole-5-carboxylic acid | 5-carboxyfuro[3,2-b]pyrrole, 1 | CHEMBL492591 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H5NO3 |
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| Mol. Mass. | 151.1195 |
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| SMILES | OC(=O)c1cc2occc2[nH]1 |
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| Structure | 
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