| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Ligand | BDBM50427835 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_940755 (CHEMBL2330135) |
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| IC50 | 151±n/a nM |
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| Citation |  Jiang, XR; Wang, P; Smith, CL; Zhu, BT Synthesis of novel estrogen receptor antagonists using metal-catalyzed coupling reactions and characterization of their biological activity. J Med Chem56:2779-90 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Name: | Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Synonyms: | ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | Estrogen-related receptor, beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56220.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_940755 |
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| Residue: | 508 |
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| Sequence: | MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP
MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC
EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG
GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL
TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV
YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
TPLNERGRQISPSTRTPGGQGKHLWLTM
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| BDBM50427835 |
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| n/a |
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| Name | BDBM50427835 |
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| Synonyms: | CHEMBL2326069 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H48O6 |
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| Mol. Mass. | 600.7841 |
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| SMILES | CCOC(=O)C(Cc1ccc(cc1)C#CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2CC[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12)C(=O)OCC |r| |
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| Structure | 
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