| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Ligand | BDBM50427874 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_940855 (CHEMBL2330435) |
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| IC50 | >10000±n/a nM |
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| Citation |  Lourido, S; Zhang, C; Lopez, MS; Tang, K; Barks, J; Wang, Q; Wildman, SA; Shokat, KM; Sibley, LD Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii. J Med Chem56:3068-77 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Name: | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Synonyms: | CAMK2A | CAMKA | CaM kinase II | CaM kinase II alpha | Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2a) | KCC2A_HUMAN | KIAA0968 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54093.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_25952118 |
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| Residue: | 478 |
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| Sequence: | MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA
ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH
LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
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| BDBM50427874 |
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| n/a |
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| Name | BDBM50427874 |
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| Synonyms: | CHEMBL2324596 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12N4 |
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| Mol. Mass. | 224.2612 |
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| SMILES | Cc1cccc(Cc2[nH]nc3ncncc23)c1 |
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| Structure | 
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