| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sialidase-4 |
|---|
| Ligand | BDBM50428075 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_941546 (CHEMBL2330586) |
|---|
| IC50 | 200000±n/a nM |
|---|
| Citation |  Zhang, Y; Albohy, A; Zou, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. J Med Chem56:2948-58 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sialidase-4 |
|---|
| Name: | Sialidase-4 |
|---|
| Synonyms: | NEU4 | NEUR4_HUMAN | Sialidase 4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 51579.82 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_960637 |
|---|
| Residue: | 484 |
|---|
| Sequence: | MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGT
LAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRN
AARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYR
VDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCN
ARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGP
GSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSW
TLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYS
DLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGC
CWPS
|
|
|
|---|
| BDBM50428075 |
|---|
| n/a |
|---|
| Name | BDBM50428075 |
|---|
| Synonyms: | CHEMBL2323564 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H25N3O5 |
|---|
| Mol. Mass. | 411.451 |
|---|
| SMILES | CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1CNNCc1ccc(cc1)-c1ccccc1)C(O)=O |r,c:7| |
|---|
| Structure | 
|
|---|
Search and Browse
