| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-3 |
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| Ligand | BDBM50428069 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_941547 (CHEMBL2330587) |
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| IC50 | 20000±n/a nM |
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| Citation |  Zhang, Y; Albohy, A; Zou, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. J Med Chem56:2948-58 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-3 |
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| Name: | Sialidase-3 |
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| Synonyms: | NEU3 | NEUR3_HUMAN | Sialidase 3 | Sialidase-3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48257.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_461856 |
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| Residue: | 428 |
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| Sequence: | MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRR
GLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSG
RNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYT
YYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVL
YCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSS
KDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRP
WILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGR
NPSQFKSN
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| BDBM50428069 |
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| n/a |
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| Name | BDBM50428069 |
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| Synonyms: | CHEMBL2325813 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N6O4 |
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| Mol. Mass. | 346.3412 |
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| SMILES | CC(=O)N[C@H]1[C@H](CNNc2ccccc2)OC(=C[C@@H]1N=[N+]=[N-])C(O)=O |r,c:17| |
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| Structure | 
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