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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Carbonic anhydrase 9 | ||
| Ligand | BDBM50428381 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_942103 (CHEMBL2340801) | ||
| Ki | 700±n/a nM | ||
| Citation |  Carta, F; Vullo, D; Maresca, A; Scozzafava, A; Supuran, CT Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. Bioorg Med Chem21:1564-9 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Carbonic anhydrase 9 | |||
| Name: | Carbonic anhydrase 9 | ||
| Synonyms: | CA-IX | CA9 | CAH9_HUMAN | Carbonate dehydratase IX | Carbonic anhydrase 9 (CA IX) | Carbonic anhydrase 9 (CAIX) | Carbonic anhydrase 9 precursor | Carbonic anhydrase IX (CA IX) | Carbonic anhydrase IX (CAIX) | Carbonic anhydrases IX | Carbonic anhydrases; II & IX | G250 | MN | Membrane antigen MN | RCC-associated antigen G250 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 49669.03 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Catalytic domain of human cloned isozyme was used in the assay | ||
| Residue: | 459 | ||
| Sequence: |
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| BDBM50428381 | |||
| n/a | |||
| Name | BDBM50428381 | ||
| Synonyms: | CHEMBL2333961 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H15ClNO | ||
| Mol. Mass. | 248.727 | ||
| SMILES | Cc1cc(C)[n+](c(C)c1)-c1cc(O)ccc1Cl |(71.56,-44.69,;72.9,-45.46,;74.23,-44.69,;75.56,-45.45,;76.89,-44.68,;75.57,-47,;74.23,-47.78,;74.23,-49.32,;72.9,-47.01,;76.9,-47.77,;78.22,-47,;79.56,-47.76,;80.89,-46.98,;79.56,-49.31,;78.23,-50.08,;76.9,-49.31,;75.56,-50.08,)| | ||
| Structure | 
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