| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 12 |
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| Ligand | BDBM50428490 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_943469 (CHEMBL2342409) |
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| Ki | 1.000000±n/a nM |
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| Citation |  Jogaite, V; Zubriene, A; Michailoviene, V; Gylyte, J; Morkunaite, V; Matulis, D Characterization of human carbonic anhydrase XII stability and inhibitor binding. Bioorg Med Chem21:1431-6 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 12 |
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| Name: | Carbonic anhydrase 12 |
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| Synonyms: | CA-XII | CA12 | CAH12_HUMAN | Carbonate dehydratase XII | Carbonic anhydrase | Carbonic anhydrase 12 (CA XII) | Carbonic anhydrase XII | Carbonic anhydrase XII (CA XII) | Carbonic anhydrase XII (CAXII) | Tumor antigen HOM-RCC-3.1.3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39456.00 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Catalytic domain of human cloned isozyme was used in the assay |
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| Residue: | 354 |
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| Sequence: | MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL
SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
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| BDBM50428490 |
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| n/a |
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| Name | BDBM50428490 |
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| Synonyms: | CHEMBL2335190 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12O3 |
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| Mol. Mass. | 216.2326 |
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| SMILES | CCc1ccc2ccc(=O)oc2c1C(C)=O |
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| Structure | 
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