| Reaction Details |
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 | Report a problem with these data |
| Target | NUAK family SNF1-like kinase 1 |
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| Ligand | BDBM50150778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_947948 (CHEMBL2344169) |
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| IC50 | 3200±n/a nM |
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| Citation |  Niemann, H; Lin, W; Müller, WE; Kubbutat, M; Lai, D; Proksch, P Trimeric hemibastadin congener from the marine sponge Ianthella basta. J Nat Prod76:121-5 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NUAK family SNF1-like kinase 1 |
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| Name: | NUAK family SNF1-like kinase 1 |
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| Synonyms: | ARK5 | KIAA0537 | NUAK1 | NUAK1_HUMAN | OMPHK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74326.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1451343 |
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| Residue: | 661 |
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| Sequence: | MEGAAAPVAGDRPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQET
LGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYE
VFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLK
LENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALG
VLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDI
ANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEV
MLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGV
VGPALPSTFKMEQDLCRTGVLLPSSPEAEVPGKLSPKQSATMPKKGILKKTQQRESGYYS
SPERSESSELLDSNDVMGSSIPSPSPPDPARVTSHSLSCRRKGILKHSSKYSAGTMDPAL
VSPEMPTLESLSEPGVPAEGLSRSYSRPSSVISDDSVLSSDSFDLLDLQENRPARQRIRS
CVSAENFLQIQDFEGLQNRPRPQYLKRYRNRLADSSFSLLTDMDDVTQVYKQALEICSKL
N
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| BDBM50150778 |
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| n/a |
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| Name | BDBM50150778 |
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| Synonyms: | Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin 7 | polybrominated diphenyl ether derivative |
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| Type | Small organic molecule |
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| Emp. Form. | C34H26Br4N4O8 |
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| Mol. Mass. | 938.208 |
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| SMILES | Oc1c(Br)cc2CCNC(=O)C(Cc3ccc(Oc4cc(CC(N=O)C(=O)NC=Cc5ccc(Oc1c2)c(Br)c5)cc(Br)c4O)c(Br)c3)N=O |w:29.29| |
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| Structure | 
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