| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 14 |
|---|
| Ligand | BDBM50428801 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_949340 (CHEMBL2339338) |
|---|
| Ki | 7970±n/a nM |
|---|
| Citation |  Gavernet, L; Gonzalez Funes, JL; Palestro, PH; Bruno Blanch, LE; Estiu, GL; Maresca, A; Barrios, I; Supuran, CT Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV. Bioorg Med Chem21:1410-8 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 14 |
|---|
| Name: | Carbonic anhydrase 14 |
|---|
| Synonyms: | CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37665.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human (cloned) isozyme. |
|---|
| Residue: | 337 |
|---|
| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
|
|
|
|---|
| BDBM50428801 |
|---|
| n/a |
|---|
| Name | BDBM50428801 |
|---|
| Synonyms: | CHEMBL471637 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H24N2O6S |
|---|
| Mol. Mass. | 324.394 |
|---|
| SMILES | COC(=O)[C@@H](NS(=O)(=O)N[C@@H](C(C)C)C(=O)OC)C(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
