| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 7 |
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| Ligand | BDBM50429525 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_944711 (CHEMBL2340957) |
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| Temperature | 298.15±n/a K |
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| IC50 | 12610±n/a nM |
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| Comments | extracted |
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| Citation |  Wagner, FF; Olson, DE; Gale, JP; Kaya, T; Weïwer, M; Aidoud, N; Thomas, M; Davoine, EL; Lemercier, BC; Zhang, YL; Holson, EB Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif. J Med Chem56:1772-6 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 7 |
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| Name: | Histone deacetylase 7 |
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| Synonyms: | HD7 | HDAC7 | HDAC7A | HDAC7_HUMAN | Histone acetylase 7 (HDAC7) | Histone deacetylase 7A | Human HDAC7 |
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| Type: | Chromatin regulator; hydrolase; repressor |
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| Mol. Mass.: | 102942.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WUI4 |
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| Residue: | 952 |
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| Sequence: | MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVG
PQEQELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPL
ETEGATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKE
SAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSV
APFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGG
TLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEP
LPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVV
DDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRP
LSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSR
HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD
NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNG
FAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQ
DPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRI
VVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALE
GGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQR
LASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
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| BDBM50429525 |
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| n/a |
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| Name | BDBM50429525 |
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| Synonyms: | CHEMBL2333346 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H9NO2 |
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| Mol. Mass. | 127.1412 |
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| SMILES | ONC(=O)C1=CCCC1 |t:4| |
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| Structure | 
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