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TargetP2Y purinoceptor 6
LigandBDBM50429535
Substrate/Competitorn/a
Meas. Tech.ChEMBL_945220 (CHEMBL2339546)
Ki>15000±n/a nM
Citation Chao, HTurdi, HHerpin, TFRoberge, JYLiu, YSchnur, DMPoss, MARehfuss, RHua, JWu, QPrice, LAAbell, LMSchumacher, WABostwick, JSSteinbacher, TEStewart, ABOgletree, MLHuang, CSChang, MCacace, AMArcuri, MJCelani, DWexler, RRLawrence, RM Discovery of 2-(phenoxypyridine)-3-phenylureas as small molecule P2Y1 antagonists. J Med Chem56:1704-14 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2Y purinoceptor 6
Name:P2Y purinoceptor 6
Synonyms:P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:PROTEIN
Mol. Mass.:36452.29
Organism:Homo sapiens (Human)
Description:ChEMBL_1511151
Residue:328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTR
TAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCI
SFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDL
SPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARM
AVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL
FYFTQKKFRRRPHELLQKLTAKWQRQGR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50429535
n/a
NameBDBM50429535
Synonyms:CHEMBL2333772
TypeSmall organic molecule
Emp. Form.C25H29N3O2
Mol. Mass.403.5167
SMILESCC(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(cc1)C(C)(C)C
Structure
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