| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50429825 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_949080 (CHEMBL2343733) |
|---|
| EC50 | >10000±n/a nM |
|---|
| Citation |  Nettekoven, M; Fingerle, J; Grether, U; Grüner, S; Kimbara, A; Püllmann, B; Rogers-Evans, M; Röver, S; Schuler, F; Schulz-Gasch, T; Ullmer, C Highly potent and selective cannabinoid receptor 2 agonists: initial hit optimization of an adamantyl hit series identified from high-through-put screening. Bioorg Med Chem Lett23:1177-81 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52842.52 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P47746 |
|---|
| Residue: | 473 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50429825 |
|---|
| n/a |
|---|
| Name | BDBM50429825 |
|---|
| Synonyms: | CHEMBL2338187 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H21NO |
|---|
| Mol. Mass. | 267.3654 |
|---|
| SMILES | O=C(N1CCc2ccccc12)C12CC3CC1CC(C2)C3 |TLB:18:17:14:12.11,1:11:14:19.17.16,THB:12:13:16:11.18,12:11:14.13.19:16,18:11:14:19.17.16,1:11:14.13.19:16| |
|---|
| Structure | 
|
|---|
Search and Browse
