| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50429838 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_949084 |
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| EC50 | 1000±n/a nM |
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| Citation |  Nettekoven M; Fingerle J; Grether U; Grüner S; Kimbara A; Püllmann B; Rogers-Evans M; Röver S; Schuler F; Schulz-Gasch T; Ullmer C Highly potent and selective cannabinoid receptor 2 agonists: initial hit optimization of an adamantyl hit series identified from high-through-put screening. Bioorg Med Chem Lett 23:1177-81 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2 | Cannabinoid CB2 receptor | Cannabinoid receptor | mCB2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38220.43 |
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| Organism: | MOUSE |
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| Description: | P47936 |
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| Residue: | 347 |
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| Sequence: | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILS
SRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLD
VRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYA
LRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
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| BDBM50429838 |
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| n/a |
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| Name | BDBM50429838 |
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| Synonyms: | CHEMBL2338189 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23NO2 |
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| Mol. Mass. | 297.3914 |
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| SMILES | OC12CC3CC(C1)CC(C3)(C2)C(=O)N1CCc2ccccc12 |TLB:9:8:4.3.2:6,0:1:4:7.9.8,11:8:4:2.1.6,THB:9:3:6:7.8.10,10:8:4:2.1.6,10:1:4:7.9.8| |
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| Structure | 
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