| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50429833 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_949084 (CHEMBL2343737) |
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| EC50 | 26±n/a nM |
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| Citation |  Nettekoven, M; Fingerle, J; Grether, U; Grüner, S; Kimbara, A; Püllmann, B; Rogers-Evans, M; Röver, S; Schuler, F; Schulz-Gasch, T; Ullmer, C Highly potent and selective cannabinoid receptor 2 agonists: initial hit optimization of an adamantyl hit series identified from high-through-put screening. Bioorg Med Chem Lett23:1177-81 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38220.43 |
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| Organism: | MOUSE |
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| Description: | P47936 |
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| Residue: | 347 |
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| Sequence: | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILS
SRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLD
VRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYA
LRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
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| BDBM50429833 |
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| n/a |
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| Name | BDBM50429833 |
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| Synonyms: | CHEMBL2338178 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23NO |
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| Mol. Mass. | 281.392 |
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| SMILES | O=C(N1CCc2ccccc12)C12CC3CC(CC(C3)C1)C2 |TLB:1:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| |
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| Structure | 
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