| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50429909 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_945279 (CHEMBL2340477) |
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| pH | 7±n/a |
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| Kd | 2.5±n/a nM |
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| Comments | extracted |
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| Citation |  Dudutiene, V; Zubriene, A; Smirnov, A; Gylyte, J; Timm, D; Manakova, E; Gražulis, S; Matulis, D 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. Bioorg Med Chem21:2093-106 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50429909 |
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| n/a |
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| Name | BDBM50429909 |
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| Synonyms: | CHEMBL2333409 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15F4NO2S2 |
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| Mol. Mass. | 393.419 |
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| SMILES | Cc1cc(C)c(CSc2c(F)c(F)c(c(F)c2F)S(N)(=O)=O)c(C)c1 |
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| Structure | 
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