| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Ligand | BDBM50430016 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_946301 (CHEMBL2345478) |
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| IC50 | 30±n/a nM |
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| Citation |  Gomez-Monterrey, I; Sala, M; Rusciano, MR; Monaco, S; Maione, AS; Iaccarino, G; Tortorella, P; D'Ursi, AM; Scrima, M; Carotenuto, A; De Rosa, G; Bertamino, A; Vernieri, E; Grieco, P; Novellino, E; Illario, M; Campiglia, P Characterization of a selective CaMKII peptide inhibitor. Eur J Med Chem62:425-34 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Name: | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Synonyms: | CAMK2A | CAMKA | CaM kinase II | CaM kinase II alpha | Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2a) | KCC2A_HUMAN | KIAA0968 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54093.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_25952118 |
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| Residue: | 478 |
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| Sequence: | MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA
ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH
LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
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| BDBM50430016 |
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| n/a |
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| Name | BDBM50430016 |
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| Synonyms: | CHEMBL2335444 |
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| Type | Small organic molecule |
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| Emp. Form. | C197H335N67O41S2 |
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| Mol. Mass. | 4362.322 |
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| SMILES | n/a |
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| Structure | 
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