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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase receptor TYRO3 | ||
| Ligand | BDBM50384576 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_951054 (CHEMBL2352092) | ||
| IC50 | 48±n/a nM | ||
| Citation |  Suárez, RM; Chevot, F; Cavagnino, A; Saettel, N; Radvanyi, F; Piguel, S; Bernard-Pierrot, I; Stoven, V; Legraverend, M Inhibitors of the TAM subfamily of tyrosine kinases: synthesis and biological evaluation. Eur J Med Chem61:2-25 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase receptor TYRO3 | |||
| Name: | Tyrosine-protein kinase receptor TYRO3 | ||
| Synonyms: | BYK | DTK | RSE | SKY | TIF | TYRO3 | TYRO3_HUMAN | Tyrosine-protein kinase SKY | ||
| Type: | Protein | ||
| Mol. Mass.: | 96894.13 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q06418 | ||
| Residue: | 890 | ||
| Sequence: |
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| BDBM50384576 | |||
| n/a | |||
| Name | BDBM50384576 | ||
| Synonyms: | CHEMBL2036808 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H29FN6 | ||
| Mol. Mass. | 396.5043 | ||
| SMILES | CCCCNc1ncc2c(nn(C[C@H]3CC[C@H](N)CC3)c2n1)-c1ccc(F)cc1 |r,wU:13.12,wD:16.16,(54.06,-16.98,;54.06,-18.52,;55.39,-19.29,;55.39,-20.83,;56.72,-21.6,;58.06,-20.83,;58.06,-19.29,;59.39,-18.52,;60.72,-19.28,;62.2,-18.8,;63.11,-20.06,;62.2,-21.31,;62.67,-22.78,;61.64,-23.92,;62.12,-25.38,;61.08,-26.52,;59.58,-26.2,;58.54,-27.34,;59.11,-24.73,;60.14,-23.59,;60.72,-20.83,;59.39,-21.6,;62.67,-17.34,;64.18,-17.02,;64.66,-15.56,;63.63,-14.41,;64.1,-12.95,;62.11,-14.74,;61.64,-16.2,)| | ||
| Structure | 
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