| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E synthase |
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| Ligand | BDBM50431410 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_952397 (CHEMBL2352763) |
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| IC50 | 59±n/a nM |
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| Citation |  Shiro, T; Kakiguchi, K; Takahashi, H; Nagata, H; Tobe, M Synthesis and biological evaluation of substituted imidazoquinoline derivatives as mPGES-1 inhibitors. Bioorg Med Chem21:2068-78 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E synthase |
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| Name: | Prostaglandin E synthase |
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| Synonyms: | MGST1L1 | MPGES1 | PGES | PIG12 | PTGES | PTGES_HUMAN | Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E synthase/G/H synthase 2 | Prostaglandin E2 synthase-1 ( mPGES-1) |
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| Type: | Protein |
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| Mol. Mass.: | 17112.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 152 |
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| Sequence: | MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
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| BDBM50431410 |
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| n/a |
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| Name | BDBM50431410 |
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| Synonyms: | CHEMBL2348041 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13BrClN3S |
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| Mol. Mass. | 418.738 |
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| SMILES | CCSc1nc2cc(Br)ccc2c2nc([nH]c12)-c1ccccc1Cl |
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| Structure | 
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