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TargetProliferating cell nuclear antigen
LigandBDBM18862
Substrate/Competitorn/a
Meas. Tech.ChEMBL_952429 (CHEMBL2352795)
IC50 25000±n/a nM
Citation Actis, MInoue, AEvison, BPerry, SPunchihewa, CFujii, N Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis. Bioorg Med Chem21:1972-7 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Proliferating cell nuclear antigen
Name:Proliferating cell nuclear antigen
Synonyms:Cyclin | PCNA | PCNA_HUMAN
Type:PROTEIN
Mol. Mass.:28752.86
Organism:Homo sapiens (Human)
Description:ChEMBL_952429
Residue:261
Sequence:
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTY
RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD
LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI
KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK
IADMGHLKYYLAPKIEDEEGS
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  Blast E-value cutoff:
BDBM18862
n/a
NameBDBM18862
Synonyms:2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid | CHEMBL41632 | TRIAC | Tiratricol | Triiodothyroacetic acid, 3 | US10322118, Entry Tiratricol
TypeSmall organic molecule
Emp. Form.C14H9I3O4
Mol. Mass.621.9323
SMILESOC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Structure
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