Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Cannabinoid receptor 2 | ||
Ligand | BDBM50432189 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_950672 (CHEMBL2352675) | ||
Ki | 107±n/a nM | ||
Citation | Madadi, NR; Penthala, NR; Brents, LK; Ford, BM; Prather, PL; Crooks, PA Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett23:2019-21 (2013) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 2 | |||
Name: | Cannabinoid receptor 2 | ||
Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 39690.94 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P34972 | ||
Residue: | 360 | ||
Sequence: |
| ||
BDBM50432189 | |||
n/a | |||
Name | BDBM50432189 | ||
Synonyms: | CHEMBL2346981 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H22ClN3O | ||
Mol. Mass. | 391.893 | ||
SMILES | Clc1ccc(Cn2cc(CC3=C(N=O)C4CCN3CC4)c3ccccc23)cc1 |c:10,(14.54,-59.36,;15.36,-58.05,;14.64,-56.69,;15.45,-55.39,;16.99,-55.44,;17.81,-54.14,;17.08,-52.78,;17.99,-51.53,;17.08,-50.29,;17.56,-48.82,;19.06,-48.5,;19.53,-47.05,;18.51,-45.9,;18.98,-44.44,;21.05,-46.73,;22.08,-47.88,;21.59,-49.34,;20.09,-49.66,;20.17,-48.02,;20.99,-47.96,;15.62,-50.76,;14.28,-50,;12.95,-50.77,;12.95,-52.31,;14.28,-53.08,;15.62,-52.3,;17.71,-56.8,;16.9,-58.1,)| | ||
Structure |