Reaction Details | |||
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Target | Cannabinoid receptor 2 | ||
Ligand | BDBM50432193 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_950672 (CHEMBL2352675) | ||
Ki | 2.5±n/a nM | ||
Citation | Madadi, NR; Penthala, NR; Brents, LK; Ford, BM; Prather, PL; Crooks, PA Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett23:2019-21 (2013) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 2 | |||
Name: | Cannabinoid receptor 2 | ||
Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 39690.94 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P34972 | ||
Residue: | 360 | ||
Sequence: |
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BDBM50432193 | |||
n/a | |||
Name | BDBM50432193 | ||
Synonyms: | CHEMBL2346979 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H24N2O3 | ||
Mol. Mass. | 400.4697 | ||
SMILES | COC(=O)c1ccc2c(C=C3N4CCC(CC4)C3=O)cn(Cc3ccccc3)c2c1 |w:9.8,(7.91,-37.06,;9.24,-36.29,;10.58,-37.05,;10.57,-38.6,;11.91,-36.28,;11.91,-34.74,;13.24,-33.97,;14.58,-34.73,;16.04,-34.26,;16.52,-32.79,;18.02,-32.47,;19.05,-33.63,;20.55,-33.31,;21.04,-31.85,;20.01,-30.7,;19.95,-31.93,;19.13,-32,;18.49,-31.02,;17.47,-29.87,;16.95,-35.5,;16.04,-36.75,;16.77,-38.11,;15.95,-39.42,;14.41,-39.36,;13.6,-40.66,;14.32,-42.02,;15.86,-42.07,;16.67,-40.77,;14.58,-36.28,;13.24,-37.06,)| | ||
Structure |