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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50432191 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_950673 (CHEMBL2352676) | ||
| Ki | 85±n/a nM | ||
| Citation |  Madadi, NR; Penthala, NR; Brents, LK; Ford, BM; Prather, PL; Crooks, PA Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett23:2019-21 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 52842.52 | ||
| Organism: | Mus musculus (Mouse) | ||
| Description: | P47746 | ||
| Residue: | 473 | ||
| Sequence: |
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| BDBM50432191 | |||
| n/a | |||
| Name | BDBM50432191 | ||
| Synonyms: | CHEMBL391430 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H23ClN2O | ||
| Mol. Mass. | 378.895 | ||
| SMILES | OC1C2CCN(CC2)\C1=C/c1cn(Cc2ccc(Cl)cc2)c2ccccc12 |TLB:9:8:4.3:6.7,THB:0:1:4.3:6.7,(28.32,-6.52,;28.34,-8.06,;29.63,-9.01,;29.78,-10.49,;28.71,-11.42,;28.58,-9.92,;30.35,-9.2,;31.09,-8.26,;27.24,-8.92,;25.7,-8.93,;24.94,-10.27,;25.85,-11.53,;24.94,-12.78,;25.71,-14.11,;27.25,-14.11,;28.01,-15.45,;29.55,-15.45,;30.32,-14.11,;31.86,-14.11,;29.54,-12.78,;28.01,-12.78,;23.46,-12.3,;22.13,-13.07,;20.79,-12.3,;20.8,-10.76,;22.13,-9.99,;23.46,-10.75,)| | ||
| Structure | 
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