Reaction Details | |||
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Target | Cannabinoid receptor 1 | ||
Ligand | BDBM50432195 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_950673 (CHEMBL2352676) | ||
Ki | 55±n/a nM | ||
Citation | Madadi, NR; Penthala, NR; Brents, LK; Ford, BM; Prather, PL; Crooks, PA Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett23:2019-21 (2013) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 1 | |||
Name: | Cannabinoid receptor 1 | ||
Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 | ||
Type: | Enzyme | ||
Mol. Mass.: | 52842.52 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | P47746 | ||
Residue: | 473 | ||
Sequence: |
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BDBM50432195 | |||
n/a | |||
Name | BDBM50432195 | ||
Synonyms: | CHEMBL2346977 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H21N3O | ||
Mol. Mass. | 367.443 | ||
SMILES | O=C1C2CCN(CC2)C1=Cc1cn(Cc2ccc(cc2)C#N)c2ccccc12 |w:9.11,(38.64,-12.97,;39.67,-14.11,;41.18,-13.8,;42.21,-14.95,;41.73,-16.41,;40.23,-16.73,;40.31,-15.09,;41.13,-15.03,;39.2,-15.57,;37.69,-15.89,;37.22,-17.35,;38.12,-18.6,;37.22,-19.85,;37.94,-21.21,;37.12,-22.51,;35.59,-22.46,;34.77,-23.76,;35.49,-25.12,;37.04,-25.17,;37.85,-23.87,;34.68,-26.43,;33.87,-27.74,;35.75,-19.37,;34.42,-20.15,;33.08,-19.38,;33.09,-17.84,;34.41,-17.07,;35.75,-17.83,)| | ||
Structure |