| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 2A6 |
|---|
| Ligand | BDBM7461 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_951966 (CHEMBL2354043) |
|---|
| IC50 | >25000±n/a nM |
|---|
| Citation |  Liu, J; Taylor, SF; Dupart, PS; Arnold, CL; Sridhar, J; Jiang, Q; Wang, Y; Skripnikova, EV; Zhao, M; Foroozesh, M Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1. J Med Chem56:4082-92 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 2A6 |
|---|
| Name: | Cytochrome P450 2A6 |
|---|
| Synonyms: | 1,4-cineole 2-exo-monooxygenase | 1.14.13.- | CP2A6_HUMAN | CYP2A3 | CYP2A6 | CYPIIA6 | Coumarin 7-hydroxylase | Cytochrome P450 2A6 | Cytochrome P450 IIA3 | Cytochrome P450(I) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 56514.34 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11509 |
|---|
| Residue: | 494 |
|---|
| Sequence: | MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK
ISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSN
GERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSN
VISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQL
LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFI
GGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQ
RFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEK
GQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGF
ATIPRNYTMSFLPR
|
|
|
|---|
| BDBM7461 |
|---|
| n/a |
|---|
| Name | BDBM7461 |
|---|
| Synonyms: | 5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihydroxy-2-phenyl-chromen-4-one | 5,7-dihydroxyflavone | CHEMBL117 | chrysin | cid_5281607 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H10O4 |
|---|
| Mol. Mass. | 254.2375 |
|---|
| SMILES | Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
