| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 [30-579] |
|---|
| Ligand | BDBM50432900 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_956683 (CHEMBL2379080) |
|---|
| IC50 | 7.1±n/a nM |
|---|
| Citation |  Ortar, G; Morera, E; De Petrocellis, L; Ligresti, A; Schiano Moriello, A; Morera, L; Nalli, M; Ragno, R; Pirolli, A; Di Marzo, V Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. Eur J Med Chem63:118-32 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Fatty-acid amide hydrolase 1 [30-579] |
|---|
| Name: | Fatty-acid amide hydrolase 1 [30-579] |
|---|
| Synonyms: | Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1 |
|---|
| Type: | Single-pass membrane protein; homodimer |
|---|
| Mol. Mass.: | 60474.00 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P97612 (aa 30-579) |
|---|
| Residue: | 550 |
|---|
| Sequence: | RWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSG
ELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKG
HDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWK
SSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGC
VYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGY
YETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFL
QNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQH
EIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPV
TTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVE
QLMTPQKQPS
|
|
|
|---|
| BDBM50432900 |
|---|
| n/a |
|---|
| Name | BDBM50432900 |
|---|
| Synonyms: | CHEMBL2376852 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18N6O2 |
|---|
| Mol. Mass. | 350.3745 |
|---|
| SMILES | CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(c2)C(N)=O)n1 |
|---|
| Structure | 
|
|---|
Search and Browse
