| Reaction Details |
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 | Report a problem with these data |
| Target | High affinity immunoglobulin gamma Fc receptor I |
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| Ligand | BDBM50432926 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_957252 (CHEMBL2378869) |
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| IC50 | 100±n/a nM |
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| Citation |  Purohit, MK; Scovell, I; Neschadim, A; Katsman, Y; Branch, DR; Kotra, LP Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells. Bioorg Med Chem Lett23:2324-7 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| High affinity immunoglobulin gamma Fc receptor I |
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| Name: | High affinity immunoglobulin gamma Fc receptor I |
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| Synonyms: | FCG1 | FCGR1 | FCGR1A | FCGR1_HUMAN | IGFR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42639.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1446762 |
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| Residue: | 374 |
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| Sequence: | MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPL
ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
ISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRN
TSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVG
IMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQ
LQEGVHRKEPQGAT
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| BDBM50432926 |
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| n/a |
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| Name | BDBM50432926 |
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| Synonyms: | CHEMBL2377172 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N4S2 |
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| Mol. Mass. | 378.514 |
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| SMILES | Cc1cc(SSc2cc(C)nn2-c2ccccc2)n(n1)-c1ccccc1 |
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| Structure | 
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