| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 1 |
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| Ligand | BDBM50064800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_955889 (CHEMBL2379815) |
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| IC50 | 31±n/a nM |
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| Citation |  Jung, KY; Cho, JH; Lee, JS; Kim, HJ; Kim, YC Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists. Bioorg Med Chem21:2643-50 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 1 |
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| Name: | P2X purinoceptor 1 |
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| Synonyms: | P2RX1_MOUSE | P2rx1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44863.39 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1280016 |
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| Residue: | 399 |
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| Sequence: | MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSG
LISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIMTPQQAQGHCAEN
PEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLH
EAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKILHPLCPVFSLGYVVRESG
QDFRSLAEKGGVVGITIDWECDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQN
GTNRRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGEGERDPAATSSTLGLQENMRTS
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| BDBM50064800 |
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| n/a |
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| Name | BDBM50064800 |
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| Synonyms: | 2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethyl-pyridin-2-ylazo)-benzene-1,4-disulfonic acid | CHEMBL69727 | isoPPADS | pyridoxal-alpha5-phosphate-6-azophenyl-2',5'-disulfonic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N3O12PS2 |
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| Mol. Mass. | 511.378 |
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| SMILES | Cc1nc(N=Nc2cc(ccc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O |w:4.3| |
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| Structure | 
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