| Reaction Details |
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 | Report a problem with these data |
| Target | Long-chain fatty acid transport protein 1 |
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| Ligand | BDBM50433139 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_956920 (CHEMBL2378196) |
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| IC50 | 100±n/a nM |
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| Citation |  Matsufuji, T; Ikeda, M; Naito, A; Hirouchi, M; Kanda, S; Izumi, M; Harada, J; Shinozuka, T Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett23:2560-5 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Long-chain fatty acid transport protein 1 |
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| Name: | Long-chain fatty acid transport protein 1 |
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| Synonyms: | 6.2.1.- | ACSVL5 | FATP-1 | FATP1 | Fatty acid transport protein 1 | S27A1_HUMAN | SLC27A1 | Solute carrier family 27 member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 71123.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_956920 |
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| Residue: | 646 |
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| Sequence: | MRAPGAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKTARRDLFGLSV
LIRVRLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLF
RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALI
FGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGM
DDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIG
VGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRL
AVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIR
LVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSV
FSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVY
GVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQ
KTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL
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| BDBM50433139 |
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| n/a |
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| Name | BDBM50433139 |
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| Synonyms: | CHEMBL2377622 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22FN5O2 |
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| Mol. Mass. | 359.398 |
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| SMILES | Fc1ccc(nc1)N1CCN(CC(=O)Nc2nc3CCCCc3o2)CC1 |
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| Structure | 
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