| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50433859 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_959597 (CHEMBL2382542) |
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| IC50 | 104±n/a nM |
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| Citation |  Scott, JS; Brocklehurst, KJ; Brown, HS; Clarke, DS; Coe, H; Groombridge, SD; Laber, D; MacFaul, PA; McKerrecher, D; Schofield, P Conformational restriction in a series of GPR119 agonists: differences in pharmacology between mouse and human. Bioorg Med Chem Lett23:3175-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | GP119_MOUSE | Gpr119 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37009.07 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1506420 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISG
LVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGL
VAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLL
FVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSP
FLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKF
FTSILLLLPARNRGPERTRESAYHIVTISHPELDG
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| BDBM50433859 |
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| n/a |
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| Name | BDBM50433859 |
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| Synonyms: | CHEMBL2382415 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19F3N6O3 |
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| Mol. Mass. | 448.3985 |
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| SMILES | FC(F)(F)COC(=O)N1C2CCC1CN(C2)c1ncc(OCc2ccncc2C#N)cn1 |
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| Structure | 
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