| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50433860 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_959598 (CHEMBL2382543) |
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| IC50 | 18±n/a nM |
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| Citation |  Scott, JS; Brocklehurst, KJ; Brown, HS; Clarke, DS; Coe, H; Groombridge, SD; Laber, D; MacFaul, PA; McKerrecher, D; Schofield, P Conformational restriction in a series of GPR119 agonists: differences in pharmacology between mouse and human. Bioorg Med Chem Lett23:3175-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50433860 |
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| n/a |
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| Name | BDBM50433860 |
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| Synonyms: | CHEMBL2382414 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17F3N6O3 |
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| Mol. Mass. | 422.3612 |
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| SMILES | FC(F)(F)COC(=O)N1CCN(CC1)c1ncc(OCc2ccncc2C#N)cn1 |
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| Structure | 
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