| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-3 |
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| Ligand | BDBM50331678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_960636 (CHEMBL2390089) |
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| IC50 | 80000±n/a nM |
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| Citation |  Albohy, A; Zhang, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4. ACS Med Chem Lett4:532-7 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-3 |
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| Name: | Sialidase-3 |
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| Synonyms: | NEU3 | NEUR3_HUMAN | Sialidase 3 | Sialidase-3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48257.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_461856 |
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| Residue: | 428 |
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| Sequence: | MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRR
GLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSG
RNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYT
YYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVL
YCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSS
KDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRP
WILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGR
NPSQFKSN
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| BDBM50331678 |
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| n/a |
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| Name | BDBM50331678 |
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| Synonyms: | (2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylate | CHEMBL1289650 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N4O8 |
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| Mol. Mass. | 372.3306 |
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| SMILES | CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CO)nn1)C(O)=O |r,c:7| |
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| Structure | 
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