| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-1 |
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| Ligand | BDBM50331673 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_960639 (CHEMBL2390092) |
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| IC50 | 200000±n/a nM |
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| Citation |  Albohy, A; Zhang, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4. ACS Med Chem Lett4:532-7 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-1 |
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| Name: | Sialidase-1 |
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| Synonyms: | NANH | NEU1 | NEUR1_HUMAN | Sialidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45463.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960639 |
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| Residue: | 415 |
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| Sequence: | MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM
EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST
WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS
WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW
RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD
TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET
VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
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| BDBM50331673 |
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| n/a |
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| Name | BDBM50331673 |
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| Synonyms: | (2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-(4-phenyl-1H-1,2,3-triazol-1-yl)propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylate | CHEMBL1289428 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N4O7 |
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| Mol. Mass. | 418.4006 |
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| SMILES | CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(nn1)-c1ccccc1)C(O)=O |r,c:7| |
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| Structure | 
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