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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Microtubule-associated protein tau | ||
| Ligand | BDBM50434371 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_961356 (CHEMBL2390683) | ||
| IC50 | 2600±n/a nM | ||
| Citation |  Bulic, B; Pickhardt, M; Mandelkow, E Progress and developments in tau aggregation inhibitors for Alzheimer disease. J Med Chem56:4135-55 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Microtubule-associated protein tau | |||
| Name: | Microtubule-associated protein tau | ||
| Synonyms: | MAPT | MAPTL | MTBT1 | Microtubule-associated protein tau | Neurofibrillary tangle protein | PHF-tau | Paired helical filament-tau | TAU | TAU_HUMAN | Tau Protein | ||
| Type: | Protein | ||
| Mol. Mass.: | 78928.63 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P10636 | ||
| Residue: | 758 | ||
| Sequence: |
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| BDBM50434371 | |||
| n/a | |||
| Name | BDBM50434371 | ||
| Synonyms: | AZURE A | Azure A (12) | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H14N3S | ||
| Mol. Mass. | 256.346 | ||
| SMILES | C[N+](C)=c1ccc2nc3ccc(N)cc3sc2c1 |(14.23,-9.19,;14.24,-7.65,;15.58,-6.89,;12.91,-6.88,;12.92,-5.34,;11.59,-4.55,;10.26,-5.32,;8.92,-4.54,;7.58,-5.32,;6.25,-4.56,;4.92,-5.33,;4.92,-6.87,;3.59,-7.64,;6.25,-7.64,;7.58,-6.86,;8.91,-7.64,;10.25,-6.86,;11.57,-7.64,)| | ||
| Structure | 
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