| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 5 |
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| Ligand | BDBM50435033 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_964508 (CHEMBL2393653) |
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| IC50 | >100000±n/a nM |
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| Citation |  Lo Monte, F; Kramer, T; Gu, J; Brodrecht, M; Pilakowski, J; Fuertes, A; Dominguez, JM; Plotkin, B; Eldar-Finkelman, H; Schmidt, B Structure-based optimization of oxadiazole-based GSK-3 inhibitors. Eur J Med Chem61:26-40 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 5 |
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| Name: | Cyclin-dependent kinase 5 |
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| Synonyms: | CDK5 | CDK5_HUMAN | CDKN5 | Cell division protein kinase 5 | Cyclin-dependent kinase 5 (CDK5/ p25) | Cyclin-dependent kinase 5 (CDK5/p35) | Cyclin-dependent-like kinase 5 | Cyclin-dependent-like kinase 5 (CDK5) | PSSALRE | Serine/threonine-protein kinase PSSALRE | Tau protein kinase II catalytic subunit |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33308.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 292 |
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| Sequence: | MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
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| BDBM50435033 |
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| n/a |
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| Name | BDBM50435033 |
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| Synonyms: | CHEMBL2391120 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H15N3O5S |
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| Mol. Mass. | 433.437 |
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| SMILES | [O-][N+](=O)c1cccc(c1)-c1ccc(CSc2nnc(o2)-c2ccc3OCOc3c2)cc1 |
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| Structure | 
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