| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50326719 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_964687 (CHEMBL2394479) |
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| Ki | 13±n/a nM |
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| Citation |  Smith, AL; Freeman, SM; Voll, RJ; Young, LJ; Goodman, MM Carbon-11 N-methyl alkylation of L-368,899 and in vivo PET imaging investigations for neural oxytocin receptors. Bioorg Med Chem Lett23:902-6 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM50326719 |
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| n/a |
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| Name | BDBM50326719 |
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| Synonyms: | (S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tolylpiperazin-1-ylsulfonyl)methyl)bicyclo[2.2.1]heptan-2-yl)-4-(methylsulfonyl)butanamide | CHEMBL1253853 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H42N4O5S2 |
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| Mol. Mass. | 554.765 |
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| SMILES | Cc1ccccc1N1CCN(CC1)S(=O)(=O)C[C@]12CC[C@H](C[C@@H]1NC(=O)[C@@H](N)CCS(C)(=O)=O)C2(C)C |r,TLB:23:22:34:18.19| |
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| Structure | 
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