| Reaction Details |
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 | Report a problem with these data |
| Target | N-formyl peptide receptor 3 |
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| Ligand | BDBM50435896 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_963919 (CHEMBL2393754) |
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| EC50 | >50000±n/a nM |
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| Citation |  Giovannoni, MP; Schepetkin, IA; Cilibrizzi, A; Crocetti, L; Khlebnikov, AI; Dahlgren, C; Graziano, A; Dal Piaz, V; Kirpotina, LN; Zerbinati, S; Vergelli, C; Quinn, MT Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. Eur J Med Chem64:512-28 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-formyl peptide receptor 3 |
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| Name: | N-formyl peptide receptor 3 |
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| Synonyms: | FML2_HUMAN | FPR3 | FPR3_HUMAN | FPRH1 | FPRL2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39971.00 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_580003 |
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| Residue: | 353 |
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| Sequence: | METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVN
TICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIA
LDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNF
AFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPL
RVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPI
LYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
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| BDBM50435896 |
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| n/a |
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| Name | BDBM50435896 |
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| Synonyms: | CHEMBL2391447 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21BrN4O4 |
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| Mol. Mass. | 485.331 |
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| SMILES | COc1ccc(Nc2c(C(C)=O)c(C)nn(CC(=O)Nc3ccc(Br)cc3)c2=O)cc1 |
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| Structure | 
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