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TargetN-formyl peptide receptor 3
LigandBDBM50435919
Substrate/Competitorn/a
Meas. Tech.ChEMBL_963919 (CHEMBL2393754)
EC50>50000±n/a nM
Citation Giovannoni, MPSchepetkin, IACilibrizzi, ACrocetti, LKhlebnikov, AIDahlgren, CGraziano, ADal Piaz, VKirpotina, LNZerbinati, SVergelli, CQuinn, MT Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. Eur J Med Chem64:512-28 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
N-formyl peptide receptor 3
Name:N-formyl peptide receptor 3
Synonyms:FML2_HUMAN | FPR3 | FPR3_HUMAN | FPRH1 | FPRL2
Type:PROTEIN
Mol. Mass.:39971.00
Organism:Homo sapiens (Human)
Description:ChEMBL_580003
Residue:353
Sequence:
METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVN
TICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIA
LDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNF
AFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPL
RVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPI
LYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
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  Blast E-value cutoff:
BDBM50435919
n/a
NameBDBM50435919
Synonyms:CHEMBL2391273
TypeSmall organic molecule
Emp. Form.C26H21BrFN3O3
Mol. Mass.522.366
SMILESCOc1ccc(Cc2cc(nn(CC(=O)Nc3ccc(Br)cc3)c2=O)-c2ccc(F)cc2)cc1
Structure
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