Reaction Details |
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Target | DNA polymerase beta |
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Ligand | BDBM38549 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_964288 (CHEMBL2395402) |
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IC50 | 9000±n/a nM |
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Citation | Funke, M; Thimm, D; Schiedel, AC; Müller, CE 8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35. J Med Chem56:5182-97 (2013) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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DNA polymerase beta |
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Name: | DNA polymerase beta |
Synonyms: | DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB |
Type: | Protein |
Mol. Mass.: | 38188.76 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 335 |
Sequence: | MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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BDBM38549 |
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n/a |
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Name | BDBM38549 |
Synonyms: | 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazino]ethoxy]ethanol | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]ethanol | 4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid | 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-2-naphthoic acid | CHEMBL170358 | CHEMBL177880 | HYDROXYZINE PAMOATE | MLS000028605 | Pamoic acid | SMR000058728 | US11744839, Compound of formula 8 | cid_25096 |
Type | Small organic molecule |
Emp. Form. | C23H16O6 |
Mol. Mass. | 388.3695 |
SMILES | OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O |
Structure |
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